CHEMBL4577133


SMILES CC(=O)C1=C(O)C(=O)N(c2ccc(Br)cc2F)C1C1CCCCC1
InChIKey ARZUMHIABDHPTN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 395.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR1 CCR1 Human Chemokine A pKi 7.96 7.97 7.98 ChEMBL
CCR2 CCR2 Human Chemokine A pKi 8.22 8.23 8.25 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR1 CCR1 Human Chemokine A pIC50 6.23 6.25 6.26 ChEMBL
CCR2 CCR2 Human Chemokine A pIC50 7.52 7.54 7.57 ChEMBL