CHEMBL4584325


SMILES Cc1ccc(OCc2nc(N)nc(N3CCN(C)CC3)n2)cc1
InChIKey KNFUPQYGUNLNSF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 314.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 4.79 4.79 4.79 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.63 6.63 6.63 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 4.54 4.54 4.54 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.54 5.54 5.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database