CHEMBL4584504


SMILES Oc1ccc(-c2ccc(CNCCc3c[nH]c4cc(F)ccc34)o2)cc1
InChIKey MZAZKADMJHOUAD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 6
Molecular weight (Da) 350.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.56 5.56 5.56 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.7 8.7 8.7 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.02 7.02 7.02 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.7 6.7 6.7 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.35 6.35 6.35 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database