CHEMBL4591410


SMILES COc1ccc2[nH]cc(CCNCc3ccc(-c4cn[nH]c4)o3)c2c1
InChIKey WZHSLWWHUWNSDV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 7
Molecular weight (Da) 336.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.82 5.82 5.82 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.55 7.55 7.55 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.84 6.84 6.84 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.76 5.76 5.76 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.92 6.92 6.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database