CHEMBL4595409


SMILES CCOc1ccc(F)cc1C1CC1CNCCCSc1nnc(-c2ccccc2)n1C
InChIKey AARWZLCCVAYIQN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 11
Molecular weight (Da) 440.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 6.23 6.23 6.23 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.3 6.3 6.3 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.53 6.53 6.53 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.66 6.66 6.66 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.18 6.18 6.18 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database