CHEMBL4597227


SMILES Nc1ncc(-c2cn(S(=O)(=O)c3ccccc3)c3ccccc23)[nH]1
InChIKey NSIHYPVKKYZWKZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 338.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.61 5.61 5.61 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.0 8.0 8.0 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.05 6.05 6.05 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.9 6.9 6.9 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.06 7.06 7.06 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database