CHEMBL466921


SMILES NC(=O)C1(c2ccc(F)cc2)CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl
InChIKey XOZUPJZIFKSWPZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 482.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.8 7.8 7.8 ChEMBL
δ OPRD Human Opioid A pKi 5.98 5.98 5.98 ChEMBL
κ OPRK Human Opioid A pKi 6.12 6.12 6.12 ChEMBL
μ OPRM Human Opioid A pKi 6.9 6.9 6.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 7.85 7.85 7.85 ChEMBL
μ OPRM Human Opioid A pEC50 6.02 6.02 6.02 ChEMBL