CHEMBL470495


SMILES CCC(=O)/N=C(/N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1
InChIKey DTIOXMCBTYZRGU-RUZDIDTESA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 5
Rotatable bonds 12
Molecular weight (Da) 529.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Y1 NPY1R Human Neuropeptide Y A pKd 8.54 8.86 8.96 ChEMBL
Y1 NPY1R Human Neuropeptide Y A pKi 8.92 8.96 9.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Y1 NPY1R Human Neuropeptide Y A pIC50 8.65 8.65 8.65 ChEMBL