CHEMBL471882


SMILES CC1(C)CCC(N2CCC3(CC2)C(=O)N(CCNCC2CCCCC2)CN3c2ccccc2)c2ccccc21
InChIKey ILOKCGSVWZJCQZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 528.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.15 9.15 9.15 ChEMBL
δ OPRD Human Opioid A pKi 5.77 5.77 5.77 ChEMBL
κ OPRK Human Opioid A pKi 7.58 7.58 7.58 ChEMBL
μ OPRM Human Opioid A pKi 6.99 6.99 6.99 ChEMBL
NOP OPRX Human Opioid A pKi 9.15 9.15 9.15 PDSP Ki database
δ OPRD Human Opioid A pKi 5.77 5.77 5.77 PDSP Ki database
κ OPRK Human Opioid A pKi 7.59 7.59 7.59 PDSP Ki database
μ OPRM Human Opioid A pKi 6.99 6.99 6.99 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database