CHEMBL472676


SMILES CC(C)N1CN(c2ccccc2)C2(CCN(C(c3ccccc3)c3ccccc3)CC2)C1=O
InChIKey XUXIHOIDTQZHEK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 439.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.18 7.18 7.18 ChEMBL
δ OPRD Human Opioid A pKi 5.04 5.04 5.04 ChEMBL
κ OPRK Human Opioid A pKi 6.26 6.26 6.26 ChEMBL
μ OPRM Human Opioid A pKi 5.39 5.39 5.39 ChEMBL
NOP OPRX Human Opioid A pKi 7.18 7.18 7.18 PDSP Ki database
κ OPRK Human Opioid A pKi 6.27 6.27 6.27 PDSP Ki database
μ OPRM Human Opioid A pKi 5.39 5.39 5.39 PDSP Ki database
δ OPRD Human Opioid A pKi 5.04 5.04 5.04 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database