CHEMBL472867


SMILES NCCN1CN(c2ccccc2)C2(CCN(C(c3ccccc3Cl)c3ccccc3Cl)CC2)C1=O
InChIKey WEJSFFXHSJTDMD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 508.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.32 7.32 7.32 ChEMBL
δ OPRD Human Opioid A pKi 7.5 7.5 7.5 ChEMBL
κ OPRK Human Opioid A pKi 6.07 6.07 6.07 ChEMBL
NOP OPRX Human Opioid A pKi 7.32 7.32 7.32 PDSP Ki database
δ OPRD Human Opioid A pKi 7.49 7.49 7.49 PDSP Ki database
κ OPRK Human Opioid A pKi 6.07 6.07 6.07 PDSP Ki database
μ OPRM Human Opioid A pKi 6.05 6.05 6.05 PDSP Ki database
μ OPRM Human Opioid A pKi 6.05 6.05 6.05 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database