CHEMBL474283


SMILES CC1(C)CCC(N2CCC3(CC2)C(=O)N(CCO)CN3c2ccccc2)c2ccccc21
InChIKey WKHQHQNKNHJSFM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 433.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.77 8.77 8.77 ChEMBL
δ OPRD Human Opioid A pKi 5.58 5.58 5.58 ChEMBL
κ OPRK Human Opioid A pKi 6.18 6.18 6.18 ChEMBL
μ OPRM Human Opioid A pKi 7.23 7.23 7.23 ChEMBL
NOP OPRX Human Opioid A pKi 8.77 8.77 8.77 PDSP Ki database
δ OPRD Human Opioid A pKi 5.58 5.58 5.58 PDSP Ki database
κ OPRK Human Opioid A pKi 6.18 6.18 6.18 PDSP Ki database
μ OPRM Human Opioid A pKi 7.23 7.23 7.23 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database