CHEMBL4744007


SMILES COc1ccc2cc(S(=O)(=O)N[C@@H]3CCN(CCCc4noc5ccccc45)C3)ccc2c1
InChIKey QVZCCZRTVHTBPK-HXUWFJFHSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 465.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.93 6.93 6.93 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.41 7.41 7.41 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.03 9.03 9.03 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.51 8.51 8.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database