CHEMBL4753511


SMILES CC(C)n1nc2c(c1-c1ccc(F)cc1)CCNCC2
InChIKey RBYJHELKTYHZNG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 273.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 8.1 8.1 8.1 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.6 7.66 7.72 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.3 7.3 7.31 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.1 8.1 8.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 7.0 7.0 7.0 ChEMBL