CHEMBL4776225


SMILES O=S(=O)(N[C@H]1CCN(CCCc2noc3ccccc23)C1)c1cccc2ccccc12
InChIKey PUHAZBKUVIJPMC-IBGZPJMESA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 435.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.14 8.14 8.14 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.59 8.59 8.59 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.96 8.96 8.96 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.49 7.49 7.49 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database