CHEMBL478680


SMILES COc1ccccc1N1CCN(CCCn2c(=O)[nH]c3ccccc32)CC1
InChIKey YERGVXFJQYPXLJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 366.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.4 7.94 8.47 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.4 7.4 7.4 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.47 8.47 8.47 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database