CHEMBL4802393


SMILES Fc1ccc(CCCCN2CCN(c3cccc(-c4ccccc4)n3)CC2)cc1
InChIKey WCTUBAYTZGGHLK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 389.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.8 6.8 6.8 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.08 7.08 7.08 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.53 5.53 5.53 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.2 7.22 7.24 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.58 6.58 6.58 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.81 6.81 6.81 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.19 6.19 6.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database