CHEMBL480425


SMILES CC1(N2CCC(n3c(-c4cccc(OCCO)c4)nc4ccccc43)CC2)CCCCCCC1
InChIKey LQDNZHDYOIKMCY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 461.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.52 9.52 9.52 ChEMBL
δ OPRD Human Opioid A pKi 8.02 8.02 8.02 ChEMBL
κ OPRK Human Opioid A pKi 7.37 7.37 7.37 ChEMBL
μ OPRM Human Opioid A pKi 7.96 7.96 7.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 8.59 8.59 8.59 ChEMBL
κ OPRK Human Opioid A pEC50 7.32 7.32 7.32 ChEMBL