CHEMBL481366


SMILES CC1(N2CCC(n3c([C@H]4CCCNC4)nc4ccccc43)CC2)CCCCCCC1
InChIKey CYYNMPPFEJPBJD-NRFANRHFSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 408.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 10.0 10.0 10.0 ChEMBL
δ OPRD Human Opioid A pKi 6.78 6.78 6.78 ChEMBL
κ OPRK Human Opioid A pKi 8.04 8.04 8.04 ChEMBL
μ OPRM Human Opioid A pKi 9.23 9.23 9.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 5.61 7.83 10.6 ChEMBL
δ OPRD Human Opioid A pEC50 6.29 6.29 6.29 ChEMBL
κ OPRK Human Opioid A pEC50 8.08 8.08 8.08 ChEMBL
μ OPRM Human Opioid A pEC50 7.64 7.64 7.64 ChEMBL