CHEMBL484345


SMILES NCCC(=O)Nc1cccc2c1cnn2S(=O)(=O)c1cccc2ccccc12
InChIKey FGFHKVYAKOQWLG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 394.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.29 5.29 5.29 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.1 8.1 8.1 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.81 6.81 6.81 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.19 5.19 5.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 7.96 7.96 7.96 ChEMBL