CHEMBL5191557


SMILES Nc1nc(N)nc(NCCCCCN2CCN(c3cccc(Cl)c3Cl)CC2)n1
InChIKey CYVSYTNDELGUJS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 8
Molecular weight (Da) 424.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.55 6.55 6.55 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.77 7.77 7.77 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.3 8.3 8.3 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.1 8.1 8.1 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.46 6.46 6.46 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database