CHEMBL4852622


SMILES Cc1ccc(-c2n[nH]cc2N2CCNCC2)cc1
InChIKey DRCWJTXHIZFXIO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 242.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 5.91 5.91 5.91 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.86 5.86 5.86 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.49 6.49 6.49 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.57 7.58 7.6 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.18 6.18 6.18 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.35 6.35 6.35 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.93 6.93 6.93 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.79 5.79 5.79 ChEMBL