CHEMBL4854456


SMILES O=C1c2cc(Cl)c(Cl)cc2CC1CCN1CCN(c2ccccn2)CC1
InChIKey PKODMLACMGNJDC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 389.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.64 7.64 7.64 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.34 7.34 7.35 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.78 5.78 5.78 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.15 6.15 6.15 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.8 6.8 6.8 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.33 7.33 7.34 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.51 5.51 5.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database