CHEMBL4854625


SMILES COc1ccc2nc(OC)n(CCNC(C)=O)c2c1
InChIKey OSKMTHQTYBZVLY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 263.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MT2 MTR1B Human Melatonin A pKi 8.51 8.51 8.51 ChEMBL
MT1 MTR1A Human Melatonin A pKi 8.92 8.92 8.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MT2 MTR1B Human Melatonin A pEC50 9.28 9.28 9.28 ChEMBL
MT1 MTR1A Human Melatonin A pEC50 9.7 10.04 10.38 ChEMBL