CHEMBL4859988


SMILES CC(=O)Nc1ccc(CCCCN2CCN(c3ccccn3)CC2)cc1
InChIKey KQZXADGECOXBKU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 352.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.87 6.87 6.87 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.62 6.62 6.62 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.69 6.69 6.69 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.42 6.44 6.45 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.84 7.84 7.85 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.71 5.71 5.71 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database