CHEMBL5204021


SMILES Cn1ccnc1SC[C@H]1CCN(S(=O)(=O)c2ccc3c(c2)CCO3)C[C@@H]1F
InChIKey MWXZKSDFCSPEBK-ZBFHGGJFSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 411.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Rat Acetylcholine (muscarinic) A pKi 7.17 7.17 7.17 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Rat Acetylcholine (muscarinic) A pIC50 6.9 6.9 6.9 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A pIC50 8.66 8.66 8.66 ChEMBL
M5 ACM5 Human Acetylcholine (muscarinic) A pIC50 7.44 7.44 7.45 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pIC50 5.36 5.36 5.36 ChEMBL