CHEMBL4860754


SMILES COc1ccccc1N1CCN(CCCCCN2C(=O)c3ccccc3S2(=O)=O)CC1
InChIKey AAQUEQYOKSKIDA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 443.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.9 6.9 6.9 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.7 5.7 5.7 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.23 6.23 6.23 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.52 8.52 8.52 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.7 7.7 7.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database