CHEMBL4862745


SMILES c1ccc(-c2n[nH]cc2N2CCNCC2)cc1
InChIKey RUQQBOVFRBIOBE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 228.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.11 7.11 7.11 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.73 6.73 6.73 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.19 6.19 6.19 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.85 6.85 6.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.34 5.34 5.34 ChEMBL