CHEMBL4866412


SMILES Fc1cccc(-c2n[nH]cc2N2CCCNCC2)c1
InChIKey XBNNPPLRTCDVRJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 260.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.6 5.6 5.6 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.64 7.64 7.65 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.08 6.08 6.08 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.84 5.84 5.84 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.61 5.61 5.61 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.08 6.08 6.08 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.61 5.61 5.61 ChEMBL