CHEMBL5222597


SMILES CC1(C)CN([C@@H]2C[C@@H](c3ccccc3)c3ccc(Cl)cc32)CCN1
InChIKey FBCSWIXKXHSYBN-AZUAARDMSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 340.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 9.17 9.17 9.17 ChEMBL
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pKi 6.18 6.18 6.18 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 7.96 7.96 7.96 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.46 7.46 7.46 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.8 6.8 6.8 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.96 7.96 7.96 ChEMBL
H1 HRH1 Human Histamine A pKi 8.18 8.18 8.18 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.96 7.96 7.96 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.89 7.89 7.89 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 5.6 5.6 5.6 ChEMBL
D1 DRD1 Human Dopamine A pKi 9.0 9.0 9.0 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 9.14 9.14 9.14 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 9.41 9.41 9.41 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.96 8.96 8.96 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.23 7.23 7.23 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.08 9.08 9.08 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.38 6.38 6.38 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.96 7.96 7.96 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 6.31 6.31 6.31 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database