CHEMBL4874069


SMILES O=C(CCCN1CCN(c2ccccn2)CC1)c1ccc2c(c1)CCC2
InChIKey OJFGNESHNMETMU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 349.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.11 7.12 7.12 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.85 7.86 7.86 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.95 6.96 6.96 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.42 6.42 6.43 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.46 6.46 6.46 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.28 8.28 8.28 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.16 6.16 6.16 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database