CHEMBL4874854


SMILES Fc1ccccc1-c1n[nH]cc1N1CCNCC1
InChIKey LCJSVVCXJQEDOV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 246.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.09 7.09 7.1 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.15 6.15 6.15 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.67 5.67 5.67 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.33 6.33 6.33 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.26 5.26 5.26 ChEMBL