CHEMBL4876545


SMILES COc1ccccc1N1CCN(Cc2ccc(CN3C(=O)c4ccccc4S3(=O)=O)cc2)CC1
InChIKey SZOQFKJMAIDYBY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 477.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.01 7.01 7.01 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.32 5.32 5.32 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.11 7.11 7.11 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.7 8.7 8.7 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.0 5.0 5.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database