CHEMBL4876743


SMILES Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NC1CCCCC1
InChIKey HINPSJCWPJZPIN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 5
Molecular weight (Da) 338.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H2 HRH2 Human Histamine A pKi 6.77 6.77 6.77 ChEMBL
H1 HRH1 Human Histamine A pKi 4.61 4.61 4.61 ChEMBL
H4 HRH4 Human Histamine A pKi 4.5 4.5 4.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H2 HRH2 Human Histamine A pEC50 6.41 6.62 6.83 ChEMBL