CHEMBL491930


SMILES O=C1OC2(CCN(C(=O)Nc3cnc(-c4ccccc4)cn3)CC2)c2ccccc21
InChIKey MKVJQAZEXGSAIT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 400.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Y5 NPY5R Human Neuropeptide Y A pKi 8.62 8.62 8.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Y5 NPY5R Rat Neuropeptide Y A pIC50 8.77 8.77 8.77 ChEMBL
Y5 NPY5R Mouse Neuropeptide Y A pIC50 8.77 8.77 8.77 ChEMBL
Y5 NPY5R Human Neuropeptide Y A pIC50 8.21 8.41 8.62 ChEMBL