CHEMBL5281830


SMILES Cn1c(CCCN2CCN(c3cccc(Cl)c3Cl)CC2)nc(-c2ccccc2)c1C(=O)NCc1ccccc1
InChIKey RDAMHUJTGOWZOX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 561.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pIC50 5.46 5.46 5.46 ChEMBL
D3 DRD3 Human Dopamine A pIC50 5.63 5.63 5.63 ChEMBL
D2 DRD2 Human Dopamine A pEC50 5.3 5.3 5.3 ChEMBL
D2 DRD2 Human Dopamine A pIC50 8.3 8.3 8.3 ChEMBL