CHEMBL494119


SMILES CC(C)c1ccccc1N1CCN(CCCCCC(=O)N2Cc3ccccc3C2)CC1
InChIKey PMNCKMIDVRPAGM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 419.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.27 7.27 7.27 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.66 7.66 7.66 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.19 7.19 7.19 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.66 7.66 7.66 PDSP Ki database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.27 7.27 7.27 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 7.19 7.19 7.19 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database