CHEMBL494458


SMILES CS(=O)(=O)Oc1ccc(CNC(=O)CCCCCN2CCN(c3ccccc3-c3ccccc3)CC2)cc1
InChIKey SAUWQAUYYQRKAV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 12
Molecular weight (Da) 535.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 8.24 8.24 8.24 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.97 6.97 6.97 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.14 6.14 6.14 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.97 6.97 6.97 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.14 6.14 6.14 PDSP Ki database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 8.24 8.24 8.24 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database