CHEMBL494512


SMILES COc1ccccc1N1CCN(CCCCCC(=O)NCc2ccc(C#N)cc2)CC1
InChIKey SNFMJRXRMXDLSC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 420.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 6.53 6.53 6.53 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.37 7.37 7.37 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.51 6.51 6.51 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.37 7.37 7.37 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.51 6.51 6.51 PDSP Ki database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 6.53 6.53 6.53 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database