CHEMBL495321


SMILES CSc1ccccc1N1CCN(CCCCCC(=O)NCc2ccncc2)CC1
InChIKey RNTITYGCQNKQBU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 412.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.46 7.46 7.46 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.09 8.09 8.09 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.19 7.19 7.19 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.09 8.09 8.09 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 7.19 7.19 7.19 PDSP Ki database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.46 7.46 7.46 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database