CHEMBL5028587


SMILES CC(=O)N[C@@H](CCCN)C(=O)NC(=O)[C@H](C)NC(=O)[C@H](CCNC(=N)N)NCCN1CCN(CCC(=O)NC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc43)CC2)CC1
InChIKey DIZOCNYCRPRXMN-LCFCVFAESA-N

Chemical properties

Hydrogen bond acceptors 13
Hydrogen bond donors 10
Rotatable bonds 21
Molecular weight (Da) 902.5

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.29 5.29 5.29 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 7.23 7.23 7.23 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 5.02 5.02 5.02 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 8.93 8.93 8.93 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 7.21 7.21 7.21 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database