CHEMBL506762


SMILES CCC[C@H]1C(=O)N([C@@H](Cc2ccc3ccccc3c2)C(=O)NC)CCN1C(=O)[C@@H](Cc1ccc(F)cc1)NC(=O)C1CCNCC1
InChIKey DZBWWVGXDVRUHV-RTOKGZNSSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 11
Molecular weight (Da) 629.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 7.77 7.77 7.77 ChEMBL
MC3 MC3R Human Melanocortin A pKi 6.9 6.9 6.9 ChEMBL
MC4 MC4R Human Melanocortin A pKi 8.28 8.28 8.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pEC50 8.0 8.0 8.0 ChEMBL
MC3 MC3R Human Melanocortin A pEC50 6.97 6.97 6.97 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 8.89 8.89 8.89 ChEMBL