CHEMBL510745


SMILES O=C1N(CCNC2CCCCC2)CN(c2ccccc2)C12CCN(C(c1ccccc1Cl)c1ccccc1Cl)CC2
InChIKey PZRQTLDSILZECV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 590.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.3 8.3 8.3 ChEMBL
δ OPRD Human Opioid A pKi 6.12 6.12 6.12 ChEMBL
κ OPRK Human Opioid A pKi 6.65 6.65 6.65 ChEMBL
μ OPRM Human Opioid A pKi 6.4 6.4 6.4 ChEMBL
NOP OPRX Human Opioid A pKi 8.3 8.3 8.3 PDSP Ki database
δ OPRD Human Opioid A pKi 6.12 6.12 6.12 PDSP Ki database
κ OPRK Human Opioid A pKi 6.65 6.65 6.65 PDSP Ki database
μ OPRM Human Opioid A pKi 6.4 6.4 6.4 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database