CHEMBL511162


SMILES CC1(C)CCC(N2CCC3(CC2)C(=O)N(CCNCc2ccccc2)CN3c2ccccc2)c2ccccc21
InChIKey GZSRIFUGJZDLKC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 522.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.44 8.44 8.44 ChEMBL
κ OPRK Human Opioid A pKi 6.82 6.82 6.82 ChEMBL
μ OPRM Human Opioid A pKi 6.86 6.86 6.86 ChEMBL
NOP OPRX Human Opioid A pKi 8.44 8.44 8.44 PDSP Ki database
δ OPRD Human Opioid A pKi 5.89 5.89 5.89 PDSP Ki database
μ OPRM Human Opioid A pKi 6.86 6.86 6.86 PDSP Ki database
δ OPRD Human Opioid A pKi 5.89 5.89 5.89 ChEMBL
κ OPRK Human Opioid A pKi 6.82 6.82 6.82 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database