CHEMBL514662


SMILES CCCNCCN1CN(c2ccccc2)C2(CCN(Cc3c(Cl)cccc3Cl)CC2)C1=O
InChIKey QDSGWTHAIXUZQT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 474.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.22 9.22 9.22 ChEMBL
δ OPRD Human Opioid A pKi 6.29 6.29 6.29 ChEMBL
κ OPRK Human Opioid A pKi 7.89 7.89 7.89 ChEMBL
μ OPRM Human Opioid A pKi 7.55 7.55 7.55 ChEMBL
NOP OPRX Human Opioid A pKi 9.22 9.22 9.22 PDSP Ki database
κ OPRK Human Opioid A pKi 7.89 7.89 7.89 PDSP Ki database
μ OPRM Human Opioid A pKi 7.55 7.55 7.55 PDSP Ki database
δ OPRD Human Opioid A pKi 6.29 6.29 6.29 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database