CHEMBL514965


SMILES C=CCN1CN(c2ccccc2)C2(CCN(C(c3ccccc3)c3ccccc3)CC2)C1=O
InChIKey PBVVKFJYSQAHNK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 437.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 6.69 6.69 6.69 ChEMBL
δ OPRD Human Opioid A pKi 4.34 4.34 4.34 ChEMBL
κ OPRK Human Opioid A pKi 6.16 6.16 6.16 ChEMBL
μ OPRM Human Opioid A pKi 4.2 4.2 4.2 ChEMBL
NOP OPRX Human Opioid A pKi 6.69 6.69 6.69 PDSP Ki database
δ OPRD Human Opioid A pKi 5.0 5.0 5.0 PDSP Ki database
κ OPRK Human Opioid A pKi 6.16 6.16 6.16 PDSP Ki database
μ OPRM Human Opioid A pKi 5.0 5.0 5.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database