CHEMBL51536


SMILES Cc1ccc(C(=O)NCN2CCN(c3ccccc3Cl)CC2)cc1
InChIKey AUCTYGBZIOGIIA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 343.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.66 7.5 7.92 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.31 7.31 7.31 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.33 6.82 7.31 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 6.66 6.66 6.66 ChEMBL