CHEMBL515829


SMILES CCCCNCCN1CN(c2ccccc2)C2(CCN(C(c3ccccc3Cl)c3ccccc3Cl)CC2)C1=O
InChIKey QWBJTXQXVHSIER-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 564.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.67 8.67 8.67 ChEMBL
δ OPRD Human Opioid A pKi 5.99 5.99 5.99 ChEMBL
μ OPRM Human Opioid A pKi 5.59 5.59 5.59 ChEMBL
NOP OPRX Human Opioid A pKi 8.67 8.67 8.67 PDSP Ki database
δ OPRD Human Opioid A pKi 5.99 5.99 5.99 PDSP Ki database
κ OPRK Human Opioid A pKi 6.78 6.78 6.78 PDSP Ki database
κ OPRK Human Opioid A pKi 6.78 6.78 6.78 ChEMBL
μ OPRM Human Opioid A pKi 5.59 5.59 5.59 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database