CHEMBL516077


SMILES COC(=O)CN1CN(c2ccccc2)C2(CCN(C(c3ccccc3Cl)c3ccccc3Cl)CC2)C1=O
InChIKey SLHIWQFTFLYARS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 537.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.71 7.71 7.71 ChEMBL
κ OPRK Human Opioid A pKi 5.64 5.64 5.64 ChEMBL
μ OPRM Human Opioid A pKi 6.17 6.17 6.17 ChEMBL
NOP OPRX Human Opioid A pKi 7.71 7.71 7.71 PDSP Ki database
δ OPRD Human Opioid A pKi 5.0 5.0 5.0 PDSP Ki database
κ OPRK Human Opioid A pKi 5.64 5.64 5.64 PDSP Ki database
μ OPRM Human Opioid A pKi 6.17 6.17 6.17 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database