CHEMBL564709


SMILES COc1ccc(N2CCN(Cc3c(C)nc4cc(C)nc(C)n34)CC2)cc1
InChIKey LPJGAZGHYONJPC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 365.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.18 5.18 5.18 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.02 6.02 6.02 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.58 6.69 6.8 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.59 6.7 6.8 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 8.07 8.07 8.07 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 8.07 8.07 8.07 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database